免疫原
Synthesized peptide derived from human CTBL1 AA range: 293-343
特异性
This antibody detects endogenous levels of CTBL1 at Human/Mouse/Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.107% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013],
功能
function:Induces apoptosis in CHO cells.,tissue specificity:Widely expressed with highest levels in skeletal muscle, placenta, heart, spleen, testis and thyroid.,
基因名称(Gene Name)
CTNNBL1 C20orf33 PP8304
其他名称
573471K9Rik;Beta catenin like 1;Beta catenin like protein 1;Beta-catenin-like protein 1;C2orf33;Cadherin associated protein;Catenin beta like 1;Chromosome 2 open reading frame 3;CTBL1_HUMAN;CTNN protein;CTNNBL 1;Ctnnbl1;dJ633O2.1;FLJ2118;NAP;Nuclear associated protein;nuclear protein NAP;Nuclear-associated protein;NYD SP19;OTTMUSP16933;P14;P14L;PP834;RP5 1118M15.1;Testis development protein NYD SP19;Testis development protein NYD-SP19;CTBL1;CTNNBL1 C20orf33 PP8304;Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (Testis development protein NYD-SP19)
细胞定位
[Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm .
组织表达
Widely expressed with highest levels in skeletal muscle, placenta, heart, spleen, testis and thyroid.