免疫原
Synthesized peptide derived from human protein . at AA range: 200-280
特异性
OPSG Polyclonal Antibody detects endogenous levels of protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness. [provided by RefSeq, Mar 2009],
功能
disease:Defects in OPN1MW are the cause of partial colorblindness deutan series (CBD) [MIM:303800]; also called deuteranopia.,function:Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.,online information:Retina International's Scientific Newsletter,PTM:Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.,tissue specificity:The three color pigments are found in the cone photoreceptor cells.,
基因名称（Gene Name）
OPN1MW GCP;OPN1MW2
蛋白名称
Medium-wave-sensitive opsin 1 (Green cone photoreceptor pigment) (Green-sensitive opsin) (GOP)
其他名称
CBBM;CBD;COD5;GCP;GOP;OPN1MW1;ML-opsin;Opn1lw;Rsvp;OPSG_HUMAN;OPN1MW;Green cone photoreceptor pigment;Green-sensitive opsin (GOP);OPSG_MOUSE;Green-sensitive opsin (M opsin);Medium wavelength-sensitive cone opsin;OPSG_RAT;Green-sensitive opsin;opsin 1;medium wave sensitive;color blindness;deutan;opsin 1 (cone pigments);medium-wave-sensitive;cone dystrophy 5 (X-linked);OPSG;OPN1MW GCP;OPN1MW2;Medium-wave-sensitive opsin 1 (Green cone photoreceptor pigment) (Green-sensitive opsin) (GOP)
细胞定位
Cell membrane ; Multi-pass membrane protein .
组织表达
The three color pigments are found in the cone photoreceptor cells.
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