免疫原
Synthesized peptide derived from human Peripherin
特异性
This antibody detects endogenous levels of Peripherin at H,R
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.12% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
背景(Background)
Peripherin(PRPH) Homo sapiens This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis.
基因名称(Gene Name)
PRPH NEF4 PRPH1
其他名称
1H10B3;NEF4;PRPH;Peripherin;PRPH NEF4 PRPH1;Peripherin (Neurofilament 4)
Fields
>>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases
细胞定位
Cytoplasm, cytoskeleton . Cell projection, axon . Perikaryon .
组织表达
Expressed in the neurons of the outer hair cells in the organ of Corti and to a lesser extent in type I spiral ganglion cells.