免疫原
The antiserum was produced against synthesized peptide derived from human NOC2L. AA range:602-651
特异性
NOC2L Polyclonal Antibody detects endogenous levels of NOC2L protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
NOC2 like nucleolar associated transcriptional repressor(NOC2L) Homo sapiens Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al., 2005 [PubMed 16322561]).[supplied by OMIM, Mar 2008],
功能
similarity:Belongs to the NOC2 family.,
蛋白名称
Nucleolar complex protein 2 homolog
其他名称
DKFZp564C186;FLJ35172;NIR;NOC2 like protein;NOC2L;Protein NOC2 homolog;Nucleolar complex protein 2 homolog;NOC2-like protein;Novel INHAT repressor
细胞定位
Nucleus, nucleoplasm. Nucleus, nucleolus. Translocates from the nucleoli to the nucleoplasm in presence of several stressors like ultraviolet irradiation and actinomycin-D. Predominantly detected in the nucleoli in non-mitotic cells. Predominantly detected in nucleoplasma in cells undergoing mitosis.
组织表达
Brain,Epithelium,Placenta,