免疫原
The antiserum was produced against synthesized peptide derived from human IFM3. AA range:1-50
特异性
IFITM3 Polyclonal Antibody detects endogenous levels of IFITM3 protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012],
功能
induction:By alpha and gamma interferons.,similarity:Belongs to the CD225 family.,
蛋白名称
Interferon-induced transmembrane protein 3
其他名称
1 8U;DSPA2b;IFITM2/3;Interferon-induced transmembrane protein 3;Interferon-inducible protein 1-8U;IFITM3;Dispanin subfamily A member 2b
细胞定位
Cell membrane ; Single-pass type II membrane protein . Late endosome membrane ; Single-pass type II membrane protein . Early endosome membrane ; Single-pass type II membrane protein. Lysosome membrane ; Single-pass type II membrane protein . Cytoplasm, perinuclear region . Co-localizes with BRI3 isoform 1 at the perinuclear region. .
组织表达
Brain,Cervix,Vascular endothelial cell,
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