免疫原
The antiserum was produced against synthesized peptide derived from human NDUC2. AA range:51-100
特异性
NDUFC2 Polyclonal Antibody detects endogenous levels of NDUFC2 protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFC2 subunit family.,subunit:Complex I is composed of 45 different subunits.,
功能
function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFC2 subunit family.,subunit:Complex I is composed of 45 different subunits.,
蛋白名称
NADH dehydrogenase [ubiquinone] 1 subunit C2
其他名称
HLC 1;Complex I-B14.5b;Complex I B14.5b;CI-B14.5b;CI B14.5b;NDUFC2;NADH dehydrogenase [ubiquinone] 1 subunit C2;HLC1;Human lung cancer oncogene 1 protein;HLC-1;NADH-ubiquinone oxidoreductase subunit B14.5b
Fields
>>Oxidative phosphorylation;>>Metabolic pathways;>>Thermogenesis;>>Retrograde endocannabinoid signaling;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy
细胞定位
Mitochondrion inner membrane ; Single-pass membrane protein ; Matrix side .
组织表达
Kidney,Ovary,Umbilical cord blood,