免疫原
Purified recombinant fragment of human BDH1 expressed in E. Coli.
特异性
BDH1 Monoclonal Antibody detects endogenous levels of BDH1 protein.
组成（Formulation）
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/200 - 1/1000. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
Affinity purification
背景（Background）
This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008],
功能
catalytic activity:(R)-3-hydroxybutanoate + NAD(+) = acetoacetate + NADH.,enzyme regulation:Requires phosphatidylcholine as an allosteric activator for enzymatic activity.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,subunit:Homotetramer.,
蛋白名称
D-beta-hydroxybutyrate dehydrogenase;mitochondrial
其他名称
3-hydroxybutyrate dehydrogenase;BDH;D-beta-hydroxybutyrate dehydrogenase;mitochondrial;EC:1.1.1.30;SDR9C1;BDH1
Fields
>>Butanoate metabolism;>>Metabolic pathways
细胞定位
Mitochondrion inner membrane . Mitochondrion matrix .
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