免疫原
Synthesized peptide derived from human FAM16
特异性
This antibody detects endogenous levels of FAM168B at Huma
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azid
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immuno
功能
Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27
基因名称(Gene Name)
FAM168B KIAA0280L M
蛋白名称
Myelin-associated neurite-outgrowth inhibitor (Mani)
细胞定位
Cytoplasm, perinuclear region . Cell membrane ; Multi-pass membrane protein . Cell projection, axon . Expressed in neuronal cell bodies and axonal fibers.
组织表达
Expressed in the brain, within neuronal axonal fibers and associated with myelin sheets (at protein level). Expression tends to be lower in the brain of Alzheimer disease patients compared to healthy individuals (at protein level).