免疫原
The antiserum was produced against synthesized peptide derived from human RCL. AA range:1-50
特异性
RCL Polyclonal Antibody detects endogenous levels of RCL protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation. Two alternative transcripts encoding different proteins have been described. [provided by RefSeq, Jul 2008],
功能
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:May play a role during cellular proliferation and c-Myc-mediated transformation.,tissue specificity:Expression is elevated in lymphoid cells that overexpress c-Myc.,
蛋白名称
Deoxyribonucleoside 5'-monophosphate N-glycosidase
其他名称
DNPH1;2'-deoxynucleoside 5'-phosphate N-hydrolase 1;5-hydroxymethyl-dUMP N-hydrolase;c Myc responsive protein Rcl;c-Myc-responsive protein RCL;RCL;Deoxyribonucleoside 5'-monophosphate N-glycosidase;C6orf108
细胞定位
Cytoplasm . Nucleus .
组织表达
Expressed at low levels in brain, colon, lung, peripheral blood leukocytes, placenta, small intestine, and thymus. Expressed at high levels in heart, kidney, liver, skeletal muscle and spleen. Overexpressed in a significant proportion of breast cancers.
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