免疫原
The antiserum was produced against synthesized peptide derived from human ELAVL2. AA range:11-60
特异性
Hel-N1 Polyclonal Antibody detects endogenous levels of Hel-N1 protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
ELAV like RNA binding protein 2(ELAVL2) Homo sapiens The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
功能
function:Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.,similarity:Belongs to the RRM elav family.,similarity:Contains 3 RRM (RNA recognition motif) domains.,tissue specificity:Brain; neural-specific.,
其他名称
ELAV2;ELAVL 2;ELAV-like neuronal protein 1;ELAV-like protein 2;Hu-antigen B;Hel-N1;ELAVL2;HUB;Nervous system-specific RNA-binding protein Hel-N1
组织表达
Brain; neural-specific.