免疫原
Synthesized peptide derived from human GROβ AA range: 58-107
特异性
This antibody detects endogenous levels of Human GROβ
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
function:Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.,online information:CXCL2 entry,pharmaceutical:GRO-beta(5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias.,PTM:The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,
功能
chemotaxis, defense response, inflammatory response, immune response, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, behavior, locomotory behavior, response to wounding, taxis,