特异性
This antibody detects endogenous levels of Human,Mouse ITGA5 (heavy chain, Cleaved-Arg894, protein was cleaved amino acid sequence between 894-895 )
背景（Background）
function:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat. Interacts with RAB21.,
功能
cell motion, cell-substrate junction assembly, cell adhesion, heterophilic cell adhesion, leukocyte adhesion, cell surface receptor linked signal transduction, integrin-mediated signaling pathway, behavior, learning or memory, memory,response to wounding, cell-cell adhesion, cell migration, biological adhesion, cell adhesion mediated by integrin, cell-cell adhesion mediated by integrin, cell junction assembly, cell junction organization, wound healing, spreading of epidermal cells, wound healing, cell motility, neurological system process, cognition, localization of cell,
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