免疫原
The antiserum was produced against synthesized peptide derived from the N-terminal region of human CLEC11A. AA range:1-50
特异性
SCGF Polyclonal Antibody detects endogenous levels of SCGF protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008],
功能
developmental stage:In the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils.,function:Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.,online information:Stem cell growth factor,PTM:O-glycosylated. Probably sulfated on the O-glycans.,similarity:Contains 1 C-type lectin domain.,tissue specificity:Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.,
蛋白名称
C-type lectin domain family 11 member A
其他名称
CLEC11A; CLECSF3; LSLCL; SCGF; C-type lectin domain family 11 member A; C-type lectin superfamily member 3; Lymphocyte secreted C-type lectin; Stem cell growth factor; p47
细胞定位
Cytoplasm . Secreted .
组织表达
Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.
联系我们
关注我们
您当前的位置： 
说明书
成功添加到购物车
