免疫原
The antiserum was produced against synthesized peptide derived from human TNAP2. AA range:131-180
特异性
TNFα-IP 2 Polyclonal Antibody detects endogenous levels of TNFα-IP 2 protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia. [provided by RefSeq, Jul 2008],
功能
developmental stage:Differentially expressed in development and capillary tube-like formation in vitro.,function:May play a role as a mediator of inflammation and angiogenesis.,induction:By TNF-alpha and other proinflammatory factors.,similarity:Belongs to the SEC6 family.,
蛋白名称
Tumor necrosis factor alpha-induced protein 2
其他名称
TNFAIP2; Tumor necrosis factor alpha-induced protein 2; TNF alpha-induced protein 2; Primary response gene B94 protein
细胞定位
exocyst,extracellular space,
组织表达
Umbilical vein endothelial cell,