免疫原
Synthesized peptide derived from human AMPKβ2 AA range: 130-210
特异性
This antibody detects endogenous levels of Human AMPKβ2
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
function:AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone-sensitive lipase. This is a regulatory subunit, may be a positive regulator of AMPK activity. It may also serve as an adapter molecule for the catalytic alpha-subunit.,PTM:Phosphorylated when associated with the catalytic subunit.,similarity:Belongs to the 5'-AMP-activated protein kinase beta subunit family.,subunit:Heterotrimer of an alpha catalytic subunit, a beta and a gamma non-catalytic regulatory subunits.,
功能
fatty acid metabolic process, fatty acid biosynthetic process, lipid biosynthetic process, regulation of cellular ketone metabolic process, organic acid biosynthetic process, regulation of lipid metabolic process, regulation of fatty acid metabolic process, regulation of fatty acid oxidation, carboxylic acid biosynthetic process,