免疫原
Purified recombinant fragment of Rak (aa2-300) expressed in E. Coli.
特异性
Rak Monoclonal Antibody detects endogenous levels of Rak protein.
组成（Formulation）
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/200 - 1/1000. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
Affinity purification
背景（Background）
The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008],
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Restricted to cells lines derived from tissues of lymphoid, brain, breast, colon and bladder origin.,
蛋白名称
Tyrosine-protein kinase FRK
其他名称
FRK; PTK5; RAK; Tyrosine-protein kinase FRK; FYN-related kinase; Nuclear tyrosine protein kinase RAK; Protein-tyrosine kinase 5
细胞定位
Cytoplasm . Nucleus . Predominantly found in the nucleus, with a small fraction found in the cell periphery.
组织表达
Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon.
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