免疫原
Synthetic Peptide of CD2
特异性
The antibody detects endogenous CD2 proteins.
组成(Formulation)
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
稀释比例
IHC: 1:200. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
背景(Background)
The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016],
功能
function:CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.,online information:CD2 entry,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD2AP (By similarity). Interacts with PSTPIP1.,