免疫原
Purified recombinant fragment of human CD69 expressed in E. Coli.
特异性
CD69 Monoclonal Antibody detects endogenous levels of CD69 protein.
组成（Formulation）
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
Affinity purification
背景（Background）
This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011],
功能
developmental stage:Earliest inducible cell surface glycoprotein acquired during lymphoid activation.,function:Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.,induction:By antigens, mitogens or activators of PKC on the surface of T and B-lymphocytes. By interaction of IL-2 with the p75 IL-2R on the surface of NK cells.,online information:CD69,PTM:Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.,similarity:Contains 1 C-type lectin domain.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.,
蛋白名称
Early activation antigen CD69
其他名称
CD69; CLEC2C; Early activation antigen CD69; Activation inducer molecule; AIM; BL-AC/P26; C-type lectin domain family 2 member C; EA1; Early T-cell activation antigen p60; GP32/28; Leukocyte surface antigen Leu-23; MLR-3; CD antigen CD69
细胞定位
Membrane; Single-pass type II membrane protein.
组织表达
Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.
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