免疫原
The antiserum was produced against synthesized peptide derived from human RXFP3. AA range:161-210
特异性
Relaxin Receptor 3 Polyclonal Antibody detects endogenous levels of Relaxin Receptor 3 protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:Receptor for relaxin-3. Binding of the ligand inhibit cAMP accumulation.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.,
功能
function:Receptor for relaxin-3. Binding of the ligand inhibit cAMP accumulation.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.,