背景(Background)
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,domain:The Gly/Pro-rich domains may be required for an unusual geometry of interaction with ligand or substrates.,function:May be involved in cell-cell interactions and recognition.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.,similarity:Contains 1 F5/8 type C domain.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed at low levels in most adult tissues and is highest in the brain and lung. Abundant in breast carcinoma cell lines.,
功能
regulation of cell growth, regulation of cell-matrix adhesion, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell adhesion, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, sensory organ development, female pregnancy, embryo implantation, negative regulation of cell proliferation, response to organic substance, regulation of cell-substrate adhesion, phosphorylation, peptidyl-tyrosine phosphorylation, peptidyl-tyrosine modification, biological adhesion, regulation of cell adhesion, mammary gland development, regulation of growth, regulation of cell proliferation, ear development, gland development, response to protein stimulus,