免疫原
Synthesized peptide derived from the Internal region of human Slit3.
特异性
Slit3 Polyclonal Antibody detects endogenous levels of Slit3 protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],
功能
function:May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.,sequence caution:Intron retention.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,similarity:Contains 1 laminin G-like domain.,similarity:Contains 23 LRR (leucine-rich) repeats.,similarity:Contains 9 EGF-like domains.,tissue specificity:Predominantly expressed in thyroid.,