免疫原
Synthesized peptide derived from human MMS19 AA range: 653-703
特异性
This antibody detects endogenous levels of MMS19 at Human/Mouse
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:May play a role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription by interacting with ERCC2/XPD and ERCC3/XPB helicases, both subunits of NER-transcription factor TFIIH. May also function as a transcriptional coactivator of estrogen receptor (ER). May be involved in regulation of ER activity by bridging TFIIH with ER or may facilitate TFIIH-mediated phosphorylation of ER in specific promoters and cell types.,similarity:Belongs to the MET18/MMS19 family.,similarity:Contains 7 HEAT repeats.,subunit:Interacts with ERCC2/XPD, ERCC3/XPB and NCOA3/RAC3.,tissue specificity:Ubiquitously expressed with higher expression in testis.,
基因名称（Gene Name）
MMS19 MMS19L
细胞定位
Nucleus . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . In mitosis, enriched on centrosomes during prophase, localizes to the spindle during metaphase and surrounds compacted spindle midzone microtubules during telophase. .
组织表达
Ubiquitously expressed with higher expression in testis.
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