免疫原
Synthesized peptide derived from human FILA2 AA range: 402-452
特异性
This antibody detects endogenous levels of FILA2 at Human/Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
The filaggrin-like protein encoded by this gene is upregulated by calcium, proteolyzed by calpain 1, and is involved in epithelial homeostasis. The encoded protein is required for proper cornification in skin, with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact, in addition to providing a physical barrier, C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa. [provided by RefSeq, Dec 2015],
功能
similarity:Belongs to the S100-fused protein family.,similarity:Contains 10 filaggrin repeats.,similarity:Contains 2 EF-hand domains.,similarity:In the N-terminal section; belongs to the S-100 family.,
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