免疫原
Synthesized peptide derived from human SDHL AA range: 207-257
特异性
This antibody detects endogenous levels of SDHL at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. [provided by RefSeq, Jul 2008],
功能
catalytic activity:L-serine = pyruvate + NH(3).,cofactor:Pyridoxal phosphate.,pathway:Carbohydrate biosynthesis; gluconeogenesis.,similarity:Belongs to the serine/threonine dehydratase family.,subunit:Homodimer.,
Fields
>>Glycine, serine and threonine metabolism;>>Cysteine and methionine metabolism;>>Valine, leucine and isoleucine biosynthesis;>>Metabolic pathways;>>Carbon metabolism;>>Biosynthesis of amino acids