免疫原
Synthesized peptide derived from human ATL4 AA range: 78-128
特异性
This antibody detects endogenous levels of ATL4 at Human/Mouse/Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Sep 2014],
功能
caution:Although similar to members of the ADAMTS family, it lacks the metalloprotease and disintegrin-like domains which are typical of that family.,function:Positive regulation of apoptosis.,similarity:Contains 1 PLAC domain.,similarity:Contains 6 TSP type-1 domains.,subunit:Interacts with CTSB.,