免疫原
Synthesized peptide derived from human MECR AA range: 160-210
特异性
This antibody detects endogenous levels of MECR at Human/Mouse/Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
catalytic activity:Acyl-CoA + NADP(+) = trans-2,3-dehydroacyl-CoA + NADPH.,function:Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids.,similarity:Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.,subunit:Homodimer.,tissue specificity:Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung.,
基因名称(Gene Name)
MECR NBRF1 CGI-63
Fields
>>Fatty acid biosynthesis;>>Fatty acid elongation;>>Metabolic pathways;>>Fatty acid metabolism
细胞定位
[Isoform 1]: Mitochondrion .; [Isoform 2]: Cytoplasm . Nucleus .
组织表达
Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung.