免疫原
Synthetic peptide from human protein at AA range: 61-110
特异性
The antibody detects endogenous Eotaxin-2
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. [provided by RefSeq, Jul 2008],
功能
function:Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3.,online information:CCL24 entry,PTM:N-glycosylated.,similarity:Belongs to the intercrine beta (chemokine CC) family.,tissue specificity:Activated monocytes and activated T lymphocytes.,
基因名称(Gene Name)
CCL24 MPIF2 SCYA24
蛋白名称
C-C motif chemokine 24 (CK-beta-6) (Eosinophil chemotactic protein 2) (Eotaxin-2) (Myeloid progenitor inhibitory factor 2) (MPIF-2) (Small-inducible cytokine A24)
其他名称
C-C motif chemokine 24 (CK-beta-6;Eosinophil chemotactic protein 2;Eotaxin-2;Myeloid progenitor inhibitory factor 2;MPIF-2;Small-inducible cytokine A24)
Fields
>>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway
组织表达
Activated monocytes and activated T lymphocytes.