免疫原
Synthetic peptide from human protein at AA range: 61-110
特异性
The antibody detects endogenous CD300b
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).[supplied by OMIM, Mar 2008],
功能
function:Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitement of GRB2.,PTM:Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2.,similarity:Belongs to the CD300 family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with TYROBP, which enhances cell surface expression and activation properties. Interacts with GRB2 in the presence of FYN.,tissue specificity:Expressed exclusively in myeloid lineages.,
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