免疫原
Synthesized peptide derived from human TPPP (Phospho-Ser18)
特异性
This antibody detects endogenous levels of TPPP (Phospho-Ser18) at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.179% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
function:Promotes in vitro the polymerization of tubulin into double-walled tubules and polymorphic aggregates or bundled stabilized microtubules blocks. When overexpressed, inhibits mitotic spindle assembly and nuclear envelope breakdown, apparently without affecting other cellular events.,PTM:Phosphorylated by TPK II. Poor substrate for GSK3.,similarity:Belongs to the TPPP family.,subunit:May form dimers. Binds tubulin; binding is inhibited by GTP. Interacts with GSK3.,tissue specificity:Widely expressed.,
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