免疫原
Synthesized peptide derived from human Kinesin-like Protein KIF1C (Phospho Ser1092)
特异性
This antibody detects endogenous levels of Human,Mouse,Rat Kinesin-like Protein KIF1C (Phospho Ser1092)
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000;IHC-p 1:50-300
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
kinesin family member 1C(KIF1C) Homo sapiens The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. Mutations in this gene are a cause of spastic ataxia 2, autosomal recessive. [provided by RefSeq, May 2014],
功能
function:Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility.,PTM:Phosphorylated on tyrosine residues.,similarity:Belongs to the kinesin-like protein family. Unc-104 subfamily.,similarity:Contains 1 FHA domain.,similarity:Contains 1 kinesin-motor domain.,subunit:Monomer .,tissue specificity:Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.,