免疫原
Synthesized peptide derived from human DACT2 AA range: 239-289
特异性
This antibody detects endogenous levels of DACT2 at Human/Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.355% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
功能
domain:The C-terminal PDZ-binding motif may mediate interaction with the PDZ domains of DSH (Dishevelled) family proteins.,function:Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors.,similarity:Belongs to the dapper family.,