免疫原
Synthesized peptide derived from human YMEL1 AA range: 136-186
特异性
This antibody detects endogenous levels of YMEL1 at Human/Mouse/Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.353% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],
功能
cofactor:Binds 1 zinc ion per subunit .,function:Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism.,similarity:In the C-terminal section; belongs to the peptidase M41 family.,similarity:In the N-terminal section; belongs to the AAA ATPase family.,