免疫原
Synthesized peptide derived from human PGM5 AA range: 357-407
特异性
This antibody detects endogenous levels of PGM5 at Human/Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.145% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
Phosphoglucomutases (EC 5.2.2.2.), such as PGM5, are phosphotransferases involved in interconversion of glucose-1-phosphate and glucose-6-phosphate. PGM activity is essential in formation of carbohydrates from glucose-6-phosphate and in formation of glucose-6-phosphate from galactose and glycogen (Edwards et al., 1995 [PubMed 8586438]).[supplied by OMIM, Mar 2008],
功能
cofactor:Binds 1 magnesium ion per subunit .,function:Component of adherens-type cell-cell and cell-matrix junctions. Lacks phosphoglucomutase activity.,similarity:Belongs to the phosphohexose mutase family.,subcellular location:Adherens-type cellular junctions.,subunit:Interacts with cytoskeletal proteins dystrophin and utrophin.,tissue specificity:Expressed in smooth and cardiac muscle at high levels and in skeletal muscle at low level. Present in other tissues due to vascular or other smooth muscle component.,