免疫原
Synthesized peptide derived from part region of human protein
特异性
LGR5 Polyclonal Antibody detects endogenous levels of protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015],
功能
function:Orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Contains 17 LRR (leucine-rich) repeats.,tissue specificity:Expressed in skeletal muscle, placenta, spinal cord, and various region of brain.,
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