免疫原
Synthesized peptide derived from part region of human protein
特异性
CANT1 Polyclonal Antibody detects endogenous levels of protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
calcium activated nucleotidase 1(CANT1) Homo sapiens This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.[provided by RefSeq, Mar 2010],
功能
catalytic activity:A nucleoside diphosphate + H(2)O = a nucleotide + phosphate.,cofactor:Calcium.,function:Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP.,miscellaneous:Not inhibited by azide.,PTM:N-glycosylated.,similarity:Belongs to the apyrase family.,subcellular location:Processed form: Secreted.,subunit:Monomer.,tissue specificity:Widely expressed.,