免疫原
Synthesized peptide derived from human ERK5
特异性
This antibody detects endogenous levels of ERK5 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.79% sodium azide.
稀释比例
IHC-p1:50-200 ,WB 1:1000-2000
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
背景（Background）
ERK5, Mitogen-activated protein kinase 7 also known as MAP kinase 7 is an enzyme that in humans is encoded by the MAPK7 gene. MAPK7 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.
Fields
>>MAPK signaling pathway;>>Gap junction;>>IL-17 signaling pathway;>>Neurotrophin signaling pathway;>>GnRH signaling pathway;>>Oxytocin signaling pathway;>>MicroRNAs in cancer;>>Fluid shear stress and atherosclerosis
细胞定位
Cytoplasm. Nucleus. Nucleus, PML body. Translocates to the nucleus upon activation.
组织表达
Expressed in many adult tissues. Abundant in heart, placenta, lung, kidney and skeletal muscle. Not detectable in liver.
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