反应性
Human:K642;Mouse:K635;Rat:K635
免疫原
Synthesized Acetyl peptide derived from human ACSS1. at AA range: K642
特异性
This antibody detects endogenous levels of ACSS1 at Human:K642;Mouse:K635;Rat:K635, It doesn't reacte with total protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a mitochondrial acetyl-CoA synthetase enzyme. A similar protein in mice plays an important role in the tricarboxylic acid cycle by catalyzing the conversion of acetate to acetyl CoA. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
功能
catalytic activity:ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.,function:Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2).,sequence caution:Sequencing errors.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,