免疫原
The antiserum was produced against synthesized peptide derived from human Involucrin. AA range:536-585
特异性
Involucrin Polyclonal Antibody detects endogenous levels of Involucrin protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
involucrin(IVL) Homo sapiens Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008],
功能
function:Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.,PTM:Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide.,similarity:Belongs to the involucrin family.,subcellular location:Constituent of the scaffolding of the cornified envelope.,subunit:Directly or indirectly cross-linked to cornifelin (CNFN).,tissue specificity:Keratinocytes of epidermis and other stratified squamous epithelia.,
细胞定位
Cytoplasm. Constituent of the scaffolding of the cornified envelope.
组织表达
Keratinocytes of epidermis and other stratified squamous epithelia.
联系我们
关注我们
您当前的位置： 
说明书
成功添加到购物车
