免疫原
Purified recombinant fragment of human Islet-1 expressed in E. Coli.
特异性
Islet-1 Monoclonal Antibody detects endogenous levels of Islet-1 protein.
组成（Formulation）
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺（Immunogen）
Affinity purification
背景（Background）
This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008],
功能
function:Binds to one of the cis-acting domain of the insulin gene enhancer.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 2 LIM zinc-binding domains.,tissue specificity:Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.,
蛋白名称
Insulin gene enhancer protein ISL-1
其他名称
ISL1; Insulin gene enhancer protein ISL-1; Islet-1
Fields
>>Signaling pathways regulating pluripotency of stem cells
组织表达
Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.
联系我们
关注我们
您当前的位置： 
说明书
成功添加到购物车
