免疫原
Purified recombinant fragment of NPT1 expressed in E. Coli.
特异性
NPT1 Monoclonal Antibody detects endogenous levels of NPT1 protein.
组成(Formulation)
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
Affinity purification
背景(Background)
caution:It is uncertain whether Met-1 or Met-3 is the initiator.,function:Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane.,similarity:Belongs to the major facilitator superfamily. Sodium/anion cotransporter family.,subunit:Interacts with PDZK1.,tissue specificity:Expressed in kidney cortex, liver and brain but not in other tissues.,
功能
caution:It is uncertain whether Met-1 or Met-3 is the initiator.,function:Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane.,similarity:Belongs to the major facilitator superfamily. Sodium/anion cotransporter family.,subunit:Interacts with PDZK1.,tissue specificity:Expressed in kidney cortex, liver and brain but not in other tissues.,
蛋白名称
Sodium-dependent phosphate transport protein 1
其他名称
SLC17A1; NPT1; Sodium-dependent phosphate transport protein 1; Na(+)/PI cotransporter 1; Na/Pi-4; Renal Na(+)-dependent phosphate cotransporter 1; Renal sodium-dependent phosphate transport protein 1; Renal sodium-phosphate transport protei
细胞定位
Apical cell membrane ; Multi-pass membrane protein .
组织表达
Expressed in kidney cortex, liver and brain but not in other tissues.