免疫原
Purified recombinant human DBC1 protein fragments expressed in E.coli
特异性
This antibody detects endogenous levels of DBC1 and does not cross-react with related proteins
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
背景(Background)
tissue specificity:Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.,
功能
tissue specificity:Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.,
其他名称
DBCCR1;Deleted in bladder cancer protein 1;Deleted in bladder cancer protein 1 recursor; FAM5A;Protein FAM5A.
细胞定位
Nucleus . Cytoplasm . Cytoplasm, cytoskeleton, spindle . Recruited to chromatin, post-UV irradiation. Sequestered to the cytoplasm in the presence of MCC. Translocated to the cytoplasm during UV-induced apoptosis. .
组织表达
Expressed in gastric carcinoma tissue and the expression gradually increases with the progression of the carcinoma (at protein level). Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.